Minor differences in haplotype frequency estimates can produce very large differences in heterogeneity test statistics

Abstract Background Tests for association between a haplotype and disease are commonly performed using a likelihood ratio test for heterogeneity between case and control haplotype frequencies.Using data from a study of association between heroin dependence and the DRD2 gene, Charging we obtained estimated haplotype frequencies and the associated li

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Using Text Mining and Data Visualization Approaches for Investigating Mental Illness from the Perspective of Traditional Chinese Medicine

Background and Objectives.Anxiety and depressive disorders are the most prevalent mental disorders, and due to the COVID-19 pandemic, Ink more people are suffering from anxiety and depressive disorders, and a considerable fraction of COVID-19 survivors have a variety of persistent neuropsychiatric problems after the initial infection.Traditional Ch

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Clinical Arterial Peripheral Vascular Pathology Does Not Impact Short- or Long-Term Survival after Transcatheter Aortic Valve Replacement

Introduction.The dramatic changes in vascular hemodynamics after transcatheter aortic valve replacement (TAVR) are well noted.However, little postprocedural data exists on the outcomes in patients with clinical arterial peripheral vascular pathology [abdominal aortic aneurysm (AAA), carotid artery stenosis (CAS), and peripheral artery disease Hand

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